INNOVA PHARMA

Wednesday 12 February 2014

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Benefits of Glucosamine with Methylsulphonylmethane

Tuesday 11 February 2014



Glucosamine is a naturally occurring amino acid in the body. The substance that is beneficial in the cartilage repair and its formation is found to be derived from Glucosamine. Cartilage is the connective tissue that is present near the joints of the bones. Cartilage helps in maintaining flexibility and lubrication for proper joint movement. The formation of new cartilage can be enhanced by consuming Glucosamine orally. Glucosamine is a common dietary supplement, which is a non-vitamin and non-mineral used by adults.

Methylsulphonylmethane or MSM is an organo-sulphur compound that occurs naturally and is helpful in supporting the muscles and tendons of the body. MSM is used as a dietary supplement in combination with glucosamine for osteoarthritis treatment. MSM possesses anti-inflammatory characteristics, and is a precursor for glycosylated lipids and proteins. MSM is chemically similar to the compound that is commonly used for arthritis treatment, dimethylsulfoxide or DMSO. When a person consumes DMSO either orally or topically, 15 percent of the entire DMSO taken will transform into MSM. The pharmaceutical formulations of MSM are prepared to meet the problems associated with joint stiffness & swelling, joint pain, muscle pain, sprain, carpal tunnel syndrome and back pain.
According to the opinion of the scientific panel on dietetic products, allergies and nutrition on the health claims, pursuant to Article 13 of Reglulation 1924/2006, MSM can be used alone or in combination with glucosamine hydrochloride for joint maintenance. The two substances are characterized enough and they are considered beneficial for joint health and in giving support to the joints.

The combination of glucosamine, chondroitin and MSM are used as nutritional supplements by the patients suffering from osteoarthritis and inflammatory joint disorders. One of the novel treatments suggested for osteoarthritis is the combination of the three supplements mentioned above. These supplements are found to be effective in causing pain relief and relief from stiffness in the case of osteoarthritis. It is always safe to take the advice of a health care provider before anyone starts using the combination of MSM, glucosamine and chondroitin. Use of these herbal supplements is prevented when the person has diabetes, bleeding disorder, drug allergy, is overweight, is using a blood thinner like warfarin. The food and drug administration or FDA has not approved all the uses of chondroitin, glucosamine and MSM. These supplements cannot be used in place of any other drugs prescribed for the patient. They can be taken as an additional medication with the doctor’s suggestion.

One of the combinations of Glucosamine and MSM prepared for osteoarthritis is Glucosamine + MSM Tablets. These tablets constitute glucosaminesulphate, MSM, calcium and vitamin D3. This medicine is a full package for osteoarthritis patients as it helps in reducing arthritis symptoms, improve the cartilage, diminishes the fracture risks, eliminate the pain in the joints, and develop strength in the bones. The calcium helps in bone development, while vitamin D3 helps in the proper absorption of calcium. Therefore, glucosamine and MSM together can reduce the cartilage damage and maintain the tendons and cartilage in the joints. The elasticity of the connective tissue is maintained by the MSM.

Glucosamin & MSM come in various combinations. One of the preferred combinations is Diacerin 50 mg + Glucosamin 750 mg + MSM 250 mg which is available in several brands in India. Cosameg D of Innova Formulations is one of the leading brands available in Indian markets.

PREGNANCY AND MORNING SICKNESS: A GOOD SIGN IN PREGNANCY ?



Nausea and vomiting are the most common and primary signs of pregnancy. These symptoms normally start from 6th week of pregnancy and can be experienced at any time of the day. They are normally observed to terminate by the 12th week of pregnancy, though the duration might differ from woman to woman. As these symptoms go worse during mornings, the problem is termed as "Morning Sickness". The severity of the condition might differ for each and every woman. It is found that nearly 75 percent of pregnant women experience this condition in their first trimester. Among these women, 50 percent might experience both nausea and vomiting while 25 percent might experience only nausea. A few of them might not have any symptoms at all.



Morning sickness is not considered harmful to either the woman or the baby in its mild stage. If the woman suffers from severe vomiting and cannot retain the food, then the condition is termed as hyperemesis gravidarum. If hyperemesis gravidarum is not treated within a certain period, the imbalance in electrolytes and loss of nutrients can be harmful to the body. The major cause for morning sickness experienced as nausea might be enhanced hormone levels, although the exact cause is not known. A few doctors consider morning sickness as a positive sign for proper improvement of placenta. The other probable causes for morning sickness are elevated estrogen levels, increased stomach acids, enhanced fatigue and increased sense of smell.
It is uncommon for nausea to remain for long, while it might appear and disappear throughout the pregnancy. The morning sickness might be stimulated by the smell of garlic, potatoes and onions. If the person is aware of the stimulant for her sickness, she can avoid getting exposed to that stimulant. The probable reasons behind morning sickness are categorized as follows.

Sensitive gastrointestinal tract

The physiological changes during early pregnancy can cause the stomach of a woman, sensitive to those changes. Some of the research studies have found that a bacterium called Helicobacter pylori in the stomach can result in nausea and vomiting in certain women. But, this is not supported by many other studies.

Estrogen Hormone

Estrogen is the hormone that is found at higher levels in the blood of women in early pregnancy, which is doubted to be playing a role in causing morning sickness.

Stress
Nausea and vomiting in some pregnant women are assumed to result as an unusual response to stress. However, there are no sufficient research studies to support this assumption.

hCG
The hCG hormone levels are known to increase quickly during the early pregnancy. Though the influence of hCG on nausea initiation is not confirmed, hCG is doubted as one of the reasons for nausea during early pregnancy. This is probably due to the increase in levels of hCG, when the person suffers from intense nausea.
The woman suffering from nausea during pregnancy might lack nutrients as she may not be able to take balanced diet. This condition can be resolved with the intake of prenatal vitamin. The baby's health is not hindered by morning sickness as long as the pregnant mother eats a balanced diet and drinks a lot of fluids. The woman with nausea has to figure out what exactly is essential for her and the desired frequency of her meals.

Medications

Damsat Forte Tablets of Innova Formulations Private Limited which is a unique combination of Pyridoxine Hydrochloride 10 mg + Doxylamine Succinate 20 mg & Folic Acid 5 mg helps women to get relief from Morning Sickness and is highly effective in early pregnancy.
 

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